Wednesday, May 23, 2012

Scientists Turn DNA Into Rewritable Memory [Science]

DNA, the strings of chemicals which define us, acts like a kind of read-only biological data storage device. Now, though, synthetic biologists have managed to turn DNA into a form or rewritable memory, just like that in our computers. More »


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Tuesday, May 22, 2012

Leaks of papal documents are 'criminal,' Vatican charges : News ...

CWN - May 21, 2012

The Vatican has denounced the publication of secret papal documents as "a criminal act," after an Italian journalist launched a new book full of leaked correspondence.

Gianluigi Nuzzi, who helped to trigger a furor over secret Vatican memos when he exposed some documents in January, released his book His Holiness on May 19. The book consists of correspondence to and from Pope Benedict XVI.

"The Holy Father and a number of his collaborators, as well as the senders of messages addressed to him, have had their individual rights to privacy and freedom of correspondence violated," the Vatican said in an angry statement responding to the book's publication. The statement said that the public release of these confidential documents "no longer appears as a questionable--though obviously defamatory--journalistic initiative, but clearly assumes the characteristics of a criminal act."

The statement indicated that the Vatican would continue investigating the internal leaks, and could take legal action against those who published the documents.

The leaked documents obviously come from one or more Vatican officials with access to sensitive correspondence. Suspicions have centered on the Secretariat of State, especially since the leaked documents generally portray the Secretary of State, Cardinal Tarcisio Bertone, in an unfavorable light.

Pope Benedict has appointed a high-level commission, consisting of three retired cardinals, to investigate the source of the leaks. The latest embarrassing releases, and the heated Vatican response, show that the matter the Holy See now considers the issue a major concern.

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Monday, May 21, 2012

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'Ghost Recon' shoots for hardcore Facebook gaming

40 min.

Hardcore gamers tend to turn up their noses at Facebook games.?Click, click, clicking your mouse to ...?grow and harvest cauliflower? Pshaw. Where are the guns? Where are the flying bullets? Where is the blood and the blood-pumping intensity?

The publisher?behind the "Tom Clancy's Ghost Recon" military?tactical?shooting?games has set out to try and remedy that. Today Ubisoft?launched "Tom Clancy's?Ghost Recon: Commander." They call it "a?fast-paced strategic combat experience that challenges everything you know about Facebook games."

Yeah, you won't be harvesting a field full of carrots here.?

Ubisoft brought on development company Loot Drop, created by well-known?developers?Brenda Garno Brathwaite and John Romero, to create?"Commander," which is being?pitched as "a gamer's game."

That is,?"Ghost Recon:?Commander" is a tactical combat game (viewed from the top down)?in which?players develop their own "Ghost." As an elite Special Forces operator you use?stealth, guns?and some nifty gadgets?as you try to wrest command of the battlefield.?The game features 10?replayable missions with three difficulty levels,?lots o' weapons for players to choose from and a chance to engage in?some deadly?mercenary?action with your Facebook friends.

Perhaps more importantly, the Facebook gameplay ties directly?into "Tom Clancy?s Ghost Recon: Future Soldier," which launches tomorrow, May 22, on the Xbox 360 and?PlayStation 3 and in June on the PC.

Play "Ghost Recon: Commander" on Facebook?and you can unlock exclusive weapons, weapon skins and bonuses to use in "Ghost Recon: Future Soldier." Meanwhile, playing "Future Soldier" can earn you exclusive characters in?"Commander."

This kind of cross-platform gaming?integration?is something players?are seeing more and more?of. Ubisoft previously launched Facebook game "Assassin?s Creed:?Project Legacy," which tied into console game "Assassin's Creed: Brotherhood." Meanwhile bonus content and upgrades could be unlocked in?games like "Fable III" and "Crackdown 2" by playing Windows Phone games "Fable Coin Golf" and "Project Sunburst."

The thinking is, core?gamers can't always play?on their machine of first?choice -- when they're at work for instance, or on the bus. So they might just play a game on Facebook or on their phone if it advances the console or PC game they love.?

Alas, players aren't exactly giving "Commander" rave reviews here on day one. It seems bringing a more hardcore game to Facebook has its problems.

"Laggy, laggy, laggy ... unplayable!" wrote player?Christos Kalogridis on the game's Facebook page.

Jason Irons complained:?"Not everyone can afford a Alienware or Razor computer to play this game properly as only 23% own them so can you PLEASE make this for NORMAL Computers and Laptops and not for certain people!"

"We're working really hard on optimizing it," came the company's response.

However, it seems?some?players are having a better time of it.

Joshua?Cheney put his exclamation key to work writing, "Most AWESOME facebook game EVER!!!!!!!!!!!!!! good job on the game it's really FUN!!!!!!!!!"

Winda Benedetti writes about games for msnbc.com. You can follow her tweets about games and other things here on Twitter or join her in the stream here on Google+. And for more video game news and reviews be sure to check out the In-Game Facebook page right here.

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Reds to make Chapman closer

Sean Marshall has surrendered 22 hits and eight earned runs in 14 1/3 innings this year, struggling to solidify the Reds? ninth-inning role. So changes are being considered at the end of the Cincinnati ?pen.

According to John Fay of the Cincinnati Enquirer, Reds manager Dusty Baker spoke Saturday ?about switching Aroldis Chapman into the closer?s role,? and pushing Marshall back into setup duty ? something he?s far more familiar with.

?[Chapman] has been so good in the eighth,? Baker told reporters after Saturday?s 6-5 victory over the Yankees. ?Like I said, you?ve got to graduate to that position. Who knows maybe graduation time is here? We?re got to discuss it, talk about it. Matter of fact, we already talked to him about it. ? We had to revamp and come up with a Plan B. So we?ll see about Plan C.?

If Chapman starts locking down saves ? which he?s completely capable of ? and becomes the Reds? regular closer, you?d have to think Baker and Co. might just run with with the strategy. Which would, unfortunately, push the 24-year-old Cuban left-hander further away from the rotation spot where he belongs.

Chapman hasn?t allowed an earned run in 17 relief appearances this season and boasts a 38/7 K/BB ratio in 21 1/3 innings. He?s one of the most dominant pitchers in baseball and has experience with starting, and yet the Reds won?t maximize his value. It?s simple math. Justin Verlander has already pitched over 67 innings.

********************

UPDATE, 11:38 AM: It?s official, according to Fay: Chapman is the Reds? new closer.

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Sunday, May 20, 2012

Pit Bull Owners Defend Their Pets ? CBS Baltimore

BALTIMORE (WJZ) ? Maryland?s highest court ruled that pit bulls are inherently dangerous. That decision caused some landlords to evict dog owners and adoptions to scale off. As Gigi Barnett reports, some pit bull owners say there?s another side of the breed that?s rarely seen.

This is how a well-behaved pit bull really acts. It?s what Maryland breed owners want the world to know? especially Maryland?s highest court, which ruled pit bulls and pit bull mixes are inherently dangerous earlier this month.

?It?s discrimination against the breed and that?s not intelligent,? said Budd Kalaga, who owns a pit bull. ?I think facts should be apparent before a decision like that is made.?

So pet owners put their pit bulls on parade. B-More Dog? a non-profit organization? has hosted this event for the last four years at the Inner Harbor. It?s a friendly way to crush the myths about pit bulls. But this year is especially tough.

?There are thousands upon thousands of interactions people have with dogs on a daily basis and the majority of those do not end up in any sort of a dog bite,? Pauline Houliaras, president of B-More Dog, said.

The number of pit bull attacks seem to be adding up.

?He came under the gate and bit my leg,? said a five-year-old boy who was mauled by a pit bull last April.

In June, a pit bull mauled a 78-year-old Greek woman, nearly killing her. Back in 2007, 10-year-old Domenic Solesky was attacked by a pit bull in front of his Towson home.

?He grabbed my leg and started shaking me around and dragged me around the alley,? Solesky explained.

It was that case that brought the matter before the state Court of Appeals. Now, the court?s ruling would make pit bull owners much more liable if their dogs lashed out.

?There are a lot of dogs that are going to end up in shelters now and a lot of families that are going to be hurt by this,? said Pauline Houliaras, B-More Dog?s president.

B-More Dog said that instead of tough penalties against dog owners, what?s needed is more education for them and more training for the breed.

B-More Dog says it plans to fight the court?s ruling.

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Major Cancer Groups Recommend CT Scans for Lung Cancer

By Dr. VERONICA SIKKA

For the first time, several top cancer organizations are recommending that smokers and former smokers ages 55 to 74 years who have smoked at least one pack of cigarettes a day for at least 30 years get an annual low-dose CT (LDCT) ? a three dimensional X-ray ? to look for lung cancer.

The recommendations, put forth as a collaborative effort by the American Cancer Society, American College of Chest Physicians, American Society of Clinical Oncology, and National Comprehensive Cancer Network, were released this morning. They appear in the Journal of the American Medical Association.

Each year, more Americans die from lung cancer than from breast, colon, and prostate cancers combined. It has held its position for years as the second most common cancer for both sexes in the United States. Only prostate cancer is more common than lung cancer in men. Breast cancer is the most common cancer in women.

If detected early enough, lung cancer can be treated and survival chances improved. Despite this, until now there had been no formal recommendations on screening tests for this deadly cancer.

?We now have an important and critical tool to screen for the most common cancer in America, and can reduce the mortality through this screening,? says Dr. John Deeken, assistant?professor in the division of hematology/oncology at Georgetown University in Washington, D.C.

Still, the question of whether every person at high risk for lung cancer should get an annual low-dose CT scan is not so simple. Since the type of CT scan used exposes the patient to radiation, albeit a low-level dose, there is a small health risk posed by this screening.

If doctors detect a questionable cancerous mass through a CT scan, they may have evaluate it further through a minor surgery called a biopsy. In this procedure, a doctor will take a sample of the tissue for further testing to determine if the mass really is a cancer. While some of these may be cancerous, there are always a certain number which are not ? meaning that the detection and subsequent surgery may not have been technically necessary.

The new recommendation also begs the question of who will be paying for the test itself.

?The cost of LDCT is currently not covered as a standard test,? says Dr. Chao Huang, lung cancer specialist at the University of Kansas Cancer Center. ?Therefore, it is difficult to recommend this test when patients may be burdened by the cost of this test year after year.?

?The key question is when will more insurance companies, and most importantly Medicare, start paying for these screening tests,? Deeken says.

And then there is the issue of how many Americans will fall under the guidelines ? and whether the resources exist to screen all of them.

?We currently do not have the infrastructure to manage the potential number of patients that would qualify for screening,? Huang says.

These issues aside, one thing is clear: screening CTs have been shown to save lives. Dr. Keith Mortman, associate professor of clinical surgery at Georgetown University School of Medicine, explains that a major study in 2010 called the National Lung Screening Trial found a 20 percent reduction in lung cancer deaths in patients who were screened with low-dose CT scans as compared to those who got chest X-rays.

Dr. Herbert Kressel, a radiologist at Harvard Medical School, says that in light of this, the recommendation is a step in the right direction.

?Lung cancer is an important health problem with a poor prognosis when it is discovered at an advanced stage,? Kressel says. ?This study is important in further highlighting the importance of low dose CT screening for patients at high risk for lung cancer.?

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