With a plan of making product ratings social, Greentape is launching a new app that they hope will bring in-store product reviews to consumers while (hopefully) spawning more product purchases for merchants. The team is demoing this new app at TechCrunch Disrupt NY 2013.Source: http://feedproxy.google.com/~r/Techcrunch/~3/bf6gssmQBjw/
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Sony's mash-up Xperia, the SP, is taking its transparent element light show to the UK today, giving budget-minded Brits one stylish and feature-packed mobile alternative. The 4.6-inch 720p handset, which is basically a Best of... edition of the Xperia S and P with an aluminum unibody, is shipping now at T-Mobile UK for £250 outright (about $387 USD), whereas Orange and EE are offering up the device for free with qualifying plans. If you want LTE, however, you only have one carrier option and that's EE -- a choice that'll have you shackled for a two-year period. As for O2 and Three, those carriers still have the SP listed as "coming soon," but it's safe to say you won't find a better bargain than *free.
*Nothing in life is free.
Filed under: Cellphones, Wireless, Mobile, Sony
Via: Xperia Blog
Source: T-Mobile Uk, Orange, EE
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Apr. 29, 2013 ? Forecasting volcanic eruptions with success is heavily dependent on recognizing well-established patterns of pre-eruption unrest in the monitoring data. But in order to develop better monitoring procedures, it is also crucial to understand volcanic eruptions that deviate from these patterns.
New research from a team led by Carnegie's Diana Roman retrospectively documented and analyzed the period immediately preceding the 2009 eruption of the Redoubt volcano in Alaska, which was characterized by an abnormally long period of pre-eruption seismic activity that's normally associated with short-term warnings of eruption. Their work is published today by Earth and Planetary Science Letters.
Well-established pre-eruption patterns can include a gradual increase in the rate of seismic activity, a progressive alteration in the type of seismic activity, or a change in ratios of gas released. "But there are numerous cases of volcanic activity that in some way violated these common patterns of precursory unrest," Roman said. "That's why examining the unusual precursor behavior of the Redoubt eruption is so enlightening."
About six to seven months before the March 2009 eruption, Redoubt began to experience long-period seismic events, as well as shallow volcanic tremors, which intensified into a sustained tremor over the next several months. Immediately following this last development, shallow, short-period earthquakes were observed at an increased rate below the summit. In the 48 hours prior to eruption both deep and shallow earthquakes were recorded.
This behavior was unusual because precursor observations usually involve a transition from short-period to long-period seismic activity, not the other way around. What's more, seismic tremor is usually seen as a short-term warning, not something that happens months in advance. However, these same precursors were also observed during the 1989-90 Redoubt eruption, thus indicating that the unusual seismic pattern reflects some unique aspect of the volcano's magma system.
Advanced analysis of the seismic activity taking place under the volcano allowed Roman and her team to understand the changes taking place before, during, and after eruption. Their results show that the eruption was likely preceded by a protracted period of slow magma ascent, followed by a short period of rapidly increasing pressure beneath Redoubt.
Elucidating the magma processes causing these unusual precursor events could help scientists to hone their seismic forecasting, rather than just relying on the same forecasting tools they're currently using, ones that are not able to detect anomalies.
For example, using current techniques, the forecasts prior to Redoubt's 2009 eruption wavered over a period of five months, back and forth between eruption being likely within a few weeks to within a few days. If the analytical techniques used by Roman and her team had been taken into consideration, the early risk escalations might not have been issued.
"Our work shows the importance of clarifying the underlying processes driving anomalous volcanic activity. This will allow us to respond to subtle signals and increase confidence in making our forecasts." Roman said.
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ALBUQUERQUE, N.M. (AP) ? Police say a 24-year-old man stabbed four people at a Catholic church in Albuquerque as a Sunday mass was nearing its end.
Police spokesman Robert Gibbs says Lawrence Capener jumped over several pews at St. Jude Thaddeus Catholic Church around noon Sunday and walked up to the choir area where he began his attack.
The injuries to the four church-goers weren't life-threatening. All four were being treated at hospitals.
An off-duty police officer and others at the church subdued Capener and held him down until police arrived.
Some of those who were stabbed were members of the choir.
The choir's pianist, Brenda Baca King, told KRQE-TV that the attacker was looking at the lead soloist. "I just remember seeing him hurdle over the pews, hurdle over people and run towards us and I thought, 'Oh my God, this is not good,'" Baca King said.
Police described the stabbing scene as chaotic as parishioners screamed as the attack unfolded.
Gibbs says Capener was interviewed by police and was expected to face felony charges. It's not yet known whether Capener has an attorney.
Gibbs says investigators don't yet know the motive for the stabbings, whether Capener had ties to the victims or whether he regularly attended the church.
The stabbings occurred as the choir had just begun its closing hymns.
Archbishop of Santa Fe Michael Sheehan released a statement saying he was saddened by the attack.
"I pray for all who have been harmed, their families, the parishioners and that nothing like this will ever happen again," Sheehan said.
The church didn't immediately return calls seeking comment on Sunday afternoon.
Source: http://news.yahoo.com/police-4-people-stabbed-albuquerque-church-224409447.html
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Woody Guthrie legacy on display at new Oklahoma museum
TULSA, Oklahoma (Reuters) - There was no doubt in Nora Guthrie's mind where the final repository of her famous musician father's legacy would be. The Woody Guthrie Center opened on Saturday in Tulsa, allowing visitors to see the folk singer's handwritten lyrics to "This Land Is Your Land" and thousands of other lyric sheets, letters, postcards, artwork, photos, manuscripts and journals.
"Trombone Shorty" carries on New Orleans jazz tradition
NEW ORLEANS (Reuters) - Musician Troy Andrews, better known as "Trombone Shorty," witnessed his first New Orleans Jazz & Heritage Festival at age 12 - not from the viewing area but on stage. "I was playing with my brother's brass band," said Andrews, now 27.
Michael Buble mixes it up on album of standards, original songs
NEW YORK (Reuters) - With a son on the way and a new album with more original songs than ever, Michael Buble is venturing into uncharted territory without letting go of his personal or artistic roots. "To Be Loved," the 37-year-old Canadian singer's follow-up to his 2011 "Christmas" album, mixes standards inspired by jazz, Motown and even the Bee Gees, with tracks written by Buble as well as collaborations with Bryan Adams and Reese Witherspoon.
South Korean rap sensation Psy honored at Tribeca Film Festival
NEW YORK (Reuters) - South Korean rapper and Internet sensation Psy was honored as a transcultural phenomenon by the Tribeca Film Festival on Friday along with a host of other luminaries ranging from choreographer Twyla Tharp to controversial media host Glenn Beck. "Who knew, right?" Psy said as he was presented his Tribeca Disruptive Innovation Award. "Giving me this award in itself is innovation, I think."
Country singer George Jones dead at 81
WASHINGTON (Reuters) - George Jones, a classic country singer with a voice full of raw honky-tonk emotion and a life full of honky-tonk turmoil, died on Friday at age 81, his spokesman said. Jones, whose career spanned more than six decades and included hits such as "He Stopped Loving Her Today" and "Window Up Above," died at Vanderbilt University Medical Center, in Nashville.
Mamma Mia! Bookie offers odds on ABBA reunion
LONDON (Reuters) - A British bookmaker is taking bets on an ABBA comeback after singer Agnetha Faltskog hinted at a possible reunion for Sweden's most successful band. Faltskog, who has come out of retirement to release a solo album called "A", was asked by German's Die Zeit Magazine if she would be open to an ABBA reunion and she responded positively.
African diva Angelique Kidjo wins Songlines Best Artist award
LONDON (Reuters) - African diva Angelique Kidjo was named Best Artist in Songlines magazine's annual world music awards on Friday, lauded for her high-energy shows and her championing of social causes. French veterans Lo'jo, who mix French folk with African and Arabic sounds, picked up the Best Group award and the young Zimbabwean band Mokoomba was chosen as top Newcomer.
Psy knocked from top of Korean charts by 63-year-old singer
SEOUL (Reuters) - South Korean rapper Psy, whose latest video "Gentleman" tracked global megahit "Gangnam Style" by going viral on the Internet, has been knocked from the top of the music charts in his native country by a 63-year-old easy listening pop singer. "Gangnam Style", which holds the YouTube record for most views with more than 1.5 billion, catapulted the sunglassed Korean with the garish jackets to world stardom and made him one of the best-known faces to grace the growing K-pop music scene.
Documentary about deceased British singer Amy Winehouse in the works
(Reuters) - A documentary is in the works about the late British soul singer Amy Winehouse and it features previously unseen material, the film's distributor said on Wednesday. The film, which will include archival footage never seen by the public, will be directed by Briton Asif Kapadia, whose 2010 film "Senna," about Brazilian auto racer Ayrton Senna, won a BAFTA for best documentary.
Kurdish singer sparks identity debate on Arab talent show
ARBIL, Iraq (Reuters) - A singer from Iraq's Kurdistan region has made it through to the semi-final of an Arab talent contest, igniting heated debates over Iraqi identity and politicizing the popular TV show. A panel of judges praised 24-year-old Parwaz Hussein and she was voted through to the next round of "Arab Idol", in which aspiring popstars from Morocco to Bahrain compete for a recording contract.
Source: http://news.yahoo.com/us-music-summary-133156745.html
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A 74-year-old gunman killed a top official in the northern German town of Hamelin on Friday before shooting himself dead, police said.
Shots were heard shortly after 10am in the city's main administrative building, where 63-year-old Butte was later found dead along with the body of his assailant.
The attacker was not identified. Police refused to comment on media speculation that the shooter was a gun fanatic but did say that the suspect was known to officers in the area. He used a heavy-calibered revolver to shoot Butte.
Butte was married with two adult children and five grandchildren, according to his profile on the district website. By Friday afternoon, his personal website had been taken off line.
Lower Saxony's Interior Minister Boris Pistorius said in a statement that Butte's murder had left him stunned. ?He will be missed by everyone. My thoughts go to his wife and children.?
He served as a police officer, rising through the ranks to become the head of the State Crime Investigations Office of Lower Saxony from 2001 to 2005. He had served as district administrator of Hamelin-Pyrmont, an elected office, since 2005.
The town is best known for the folk tale of the Pied Piper, later popularised by the Brothers Grimm.
Gun violence is rare in Germany, although major massacres in Erfurt in 2002 and Winnenden in 2009 made headlines around the world.
Gun crime, never high in Germany when compared with many other countries, dropped considerably over the past decade ? in 2000, police registered 19,400 crimes in which involved a firearm. By 2011, this figure stood at 11,700.
Of the 2011 statistics, 5,600 were shootings and 132 were incidents in which a gun was involved in a murder, manslaughter or assisted suicide investigation.
AFP/DPA/The Local/jcw
Source: http://www.thelocal.de/society/20130426-49387.html
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VW's Buscemi-directed AmEx Unstaged show will stream live this Sunday at 9 p.m. ET/6 p.m. PT.
By James Montgomery
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Source: http://the-gadgeteer.com/2013/04/27/the-fusion-plate-two-camera-accessories-in-one-package/
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By Sami Aboudi and Eric Beech, Reuters
DUBAI -- A driver opened fire on a car driven by a U.S. citizen in northern Saudi Arabia after crashing into his vehicle, but there were no casualties, Saudi state news agency SPA reported late on Wednesday.
It was not immediately clear if the incident was a deliberate attack on the American or just a case of road rage.
"The Tabuk police received a report at around 1 p.m. (6 a.m. ET) that a car driven by a resident American citizen had been subjected to a crash and shooting from the driver of the other vehicle while driving on a road in the city of Tabuk," SPA quoted the local police chief as saying.
"There were no injuries but the car was damaged by the accident and shooting," it added.
The kingdom, a key regional U.S. ally and the world's top oil exporter, faced a campaign of attacks by al Qaeda militants targeting foreigners and government facilities between 2003 and 2006. Security forces crushed the militants, arresting and killing many and forcing others to flee the kingdom.
Copyright 2013 Thomson Reuters. Click for restrictions.news channel 9 insanity workout mass effect 3 launch trailer yelp huntsville al channel 2 news adrienne bailon
![[ Back to EurekAlert! ]](http://www.eurekalert.org/images/back2e.gif){kind=small}
Public release date: 26-Apr-2013
Share ] Contact: Matthew Swayne
mls29@psu.edu
814-865-9481
Penn State
Changing the way a plant forms cellulose may lead to more efficient, less expensive biofuel production, according to Penn State engineers.
"What every biofuel manufacturer wants to do is to get to the sugars," said Jeffrey Catchmark, associate professor of agricultural and biological engineering. "But the structure of cellulose itself can be an obstacle."
Catchmark said that most of a plant's sugar-based energy is locked up in the crystalline structure of cellulose. To make cellulose, plants create long chains of sugar -- glucose -- that are then crystallized and densely packed into tight, ordered bundles resistant to water and other solvents. This bundling may help build strong plant cell walls, but biofuel makers must use extra effort to break down and separate the bundles and the crystalline cellulose to extract the sugars used to ferment fuels.
Using bacteria that produce cellulose as a model to test the process, the researchers discovered an approach for modifying cellulose synthesis in living plants for improved biofuel-making efficiency. During the synthesis process the researchers added glucomannan, a complex carbohydrate found in plants that sticks to cellulose, and found that it altered the structure and assembly of the cellulose, allowing it to be broken down more efficiently.
Another method to ensure the glucomannan is added during cellulose formation requires genetically engineering the plant to express or over-express the enzymes that form the glucomannan, according to the researchers, who applied for a provisional patent on the process.
"In our work, what we are interested in is whether we can improve digestibility by altering the crystal structure or by altering the bundle formation," said Catchmark, who worked with Lin Fang, graduate student in agricultural and biological engineering.
By growing plants with cellulose that is less crystalized and that has fewer structured bundles, biofuel manufacturers will not need to spend as much time and effort breaking down these pre-treated plants, according to the researchers. Currently, biofuel manufacturers must use several industrial processes that are time- and energy-intensive and relatively expensive, including chemical, mechanical and fermentation, to break down the cellulose and separate other materials.
Catchmark said that biofuel manufacturers may be able to further optimize production processes to suit the modified plants for even greater efficiency.
"This will give biofuel makers more options," Catchmark said. "Hopefully, you will need less effort and lower costs with the pre-treatment, but with improved conversion efficiency."
Catchmark said that while the technique was used on bacteria, it could be adapted to various plant species because both plants and certain bacteria share similarities in how they create cellulose. He said that researchers could use the process in both grass and wood plant species, giving biofuel makers additional options. The researchers now plan to test the methods on plants.
###
The U.S. Department of Energy supported this work through the Penn State Center for Lignocellulose Structure and Formation.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 26-Apr-2013 Share ] Contact: Matthew Swayne
mls29@psu.edu
814-865-9481
Penn State
Changing the way a plant forms cellulose may lead to more efficient, less expensive biofuel production, according to Penn State engineers.
"What every biofuel manufacturer wants to do is to get to the sugars," said Jeffrey Catchmark, associate professor of agricultural and biological engineering. "But the structure of cellulose itself can be an obstacle."
Catchmark said that most of a plant's sugar-based energy is locked up in the crystalline structure of cellulose. To make cellulose, plants create long chains of sugar -- glucose -- that are then crystallized and densely packed into tight, ordered bundles resistant to water and other solvents. This bundling may help build strong plant cell walls, but biofuel makers must use extra effort to break down and separate the bundles and the crystalline cellulose to extract the sugars used to ferment fuels.
Using bacteria that produce cellulose as a model to test the process, the researchers discovered an approach for modifying cellulose synthesis in living plants for improved biofuel-making efficiency. During the synthesis process the researchers added glucomannan, a complex carbohydrate found in plants that sticks to cellulose, and found that it altered the structure and assembly of the cellulose, allowing it to be broken down more efficiently.
Another method to ensure the glucomannan is added during cellulose formation requires genetically engineering the plant to express or over-express the enzymes that form the glucomannan, according to the researchers, who applied for a provisional patent on the process.
"In our work, what we are interested in is whether we can improve digestibility by altering the crystal structure or by altering the bundle formation," said Catchmark, who worked with Lin Fang, graduate student in agricultural and biological engineering.
By growing plants with cellulose that is less crystalized and that has fewer structured bundles, biofuel manufacturers will not need to spend as much time and effort breaking down these pre-treated plants, according to the researchers. Currently, biofuel manufacturers must use several industrial processes that are time- and energy-intensive and relatively expensive, including chemical, mechanical and fermentation, to break down the cellulose and separate other materials.
Catchmark said that biofuel manufacturers may be able to further optimize production processes to suit the modified plants for even greater efficiency.
"This will give biofuel makers more options," Catchmark said. "Hopefully, you will need less effort and lower costs with the pre-treatment, but with improved conversion efficiency."
Catchmark said that while the technique was used on bacteria, it could be adapted to various plant species because both plants and certain bacteria share similarities in how they create cellulose. He said that researchers could use the process in both grass and wood plant species, giving biofuel makers additional options. The researchers now plan to test the methods on plants.
###
The U.S. Department of Energy supported this work through the Penn State Center for Lignocellulose Structure and Formation.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-04/ps-ccp042613.php
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Owning a Wii U can feel like an exercise in patience: games and apps can take up to 30 seconds to load, and downloaded software needs to be manually installed. Thankfully, Nintendo heard its fans lamentations, and has issued the first of two major updates designed to mitigate the problem. In addition to dramatically speeding up software load times, the update revises how the Wii U handles downloads and installs. Rather than manually having to install software, the system will automatically update, download and unwrap patches in the background, even if the console is powered down. The system update also puts the finishing touches on the Wii U Virtual Console, which is promised to launch officially in the coming days. Nintendo's old VC can be accessed a little quicker now, too, as the update now allows users to jump directly into the sandboxed Wii ecosystem by holding the B button during start up. All in all, a pretty solid update to a system that needs a little fixing. Check out the full list of changes after the break.
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/x568JPahOpQ/
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PARIS (Reuters) - Stock index futures pointed to a higher open on Wall Street on Thursday, with futures for the S&P 500 up 0.04 percent, Dow Jones futures up 0.16 percent and Nasdaq 100 futures up 0.15 percent at 4 a.m. ET.
Verizon Communications Inc
European stocks dipped in morning trade, halting a sharp rally started earlier in the week, as a raft of mixed corporate earnings dented investors' appetite for equities. <.eu/>
A flurry of U.S. companies were set to report results on Thursday, including Amazon.com Inc , Bristol-Myers Squibb
Chipmaker LSI Corp
U.S. life insurer Aflac Inc , which counts on Japan for almost 80 percent of its business, reported a better-than-expected 13 percent rise in quarterly profit but a weaker yen took a big chunk out of its premium income. 0dbxun>
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Source: http://news.yahoo.com/stock-index-futures-signal-slightly-higher-open-081750934--finance.html
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Today, our lives are spread across a growing array of digital devices, from smartphones and laptops to tablets and connected TVs. While each device tends to perform certain tasks better than others, as we use tablets to read books and shop, laptops for work-related tasks and smartphones to check the weather, stocks and email, increasingly, our devices are working together in concert and becoming interchangeable by keeping us connected to the cloudy Web. Yet, in spite of the fact that we live in an increasingly connected and multi-platform world, when it comes to texting, we find ourselves locked in to our phones.Source: http://feedproxy.google.com/~r/Techcrunch/~3/fWz1a_-PU68/
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Most of the hullabaloo around Sprint's nascent LTE network has focused on the consumer. But, don't worry, the carrier hasn't forgotten about its precious business customers. Today it announced that Data Link and Static IP would be coming to its latest iteration of 4G. For those of you not familiar, Data Link carries a guarantee of 99.9 percent availability -- something craved by enterprise types. And it covers not just handsets and hotspots, but kiosks, sales terminals and can even serve as a backup plan for wired service. The ability to assign a static IP address will also be welcomed by IT departments that need to tightly manage wireless devices. And, just in case you're not covered by the Now Network's LTE just yet, both services are available on 3G as well. For more, check out the PR after the break.
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/jmsMKse54rc/
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Sony is quickly developing a reputation as the tinkerer's phone maker of choice: it took on responsibility for maintaining AOSP on the Xperia S even when Google couldn't. Today, it's proving that commitment to open software by releasing an Android 4.2.2-based AOSP build for one of its 2013 flagships, the Xperia Z. The initial public version is rough and has to go without proprietary camera and cellular drivers, although it does support Bluetooth, GPS, SD storage, WiFi and a host of sensors. Developers and other experimenters can grab the necessary code on GitHub; the rest of us can stick to marginally safer CyanogenMod nightlies.
Filed under: Cellphones, Mobile, Sony, Google
Source: GitHub
Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/jg57HIcrFdg/
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LONDON (AP) ? Growing hopes that the European Central Bank will cut interest rates next month shored up markets Tuesday despite more evidence that the Chinese economy is slowing down.
After a disappointing trading session in Asia, investors, particularly in Europe, have turned increasingly confident that the ECB will decide to cut its main interest rate to a record low of 0.50 percent at its meeting next Thursday.
The latest bout of speculation over the ECB came after a survey into manufacturing conditions among the 17 European Union countries that use the euro disappointed. The PMI survey from Markit fell another 0.3 points in April to 46.5 ? anything below 50 indicates a contraction.
Despite confirmation of the recessionary conditions in the eurozone as a whole, investors piled back into stocks despite the subdued start to the day.
"This is now going to prompt talk again of an ECB rate cut, given that Bundesbank head, Jens Weidmann, conceded recently that a rate cut would be considered if we see further worsening in the economic data," said Craig Erlam, market analyst at Alpari. The Bundesbank is Germany's central bank.
In Europe, Germany's DAX rallied 2.1 percent to 7,638 while the CAC-40 in France was up 3 percent at 3,761. The FTSE 100 index of leading British shares was 1.8 percent higher at 6,392.
The market optimism helped lower interest rates on government bonds for financially weak countries like Italy and Spain.
Wall Street opened strongly too, with the Dow Jones industrial average up 0.7 percent at 14,677, while the broader S&P 500 index rose the same rate to 1,573.
A raft of earnings helped shore up the U.S. open. DuPont, the chemical maker, reported first-quarter profits that more than doubled as its agricultural unit did brisk business. Travelers insurance and Coach soared after strong reports.
The main point of interest on the earnings front will be when Apple reports after the markets close. The company has seen its share price take a battering over the past few months amid mounting concerns over its product line and tough competition.
"There will also be a lot of interest in the outlook for Apple, with the current share price reflecting the pessimism surrounding the company, compared to last year," said Alpari's Erlam.
Earlier, Chinese shares underperformed after a downbeat manufacturing survey renewed concerns over the world's second-largest economy.
A preliminary survey by HSBC Corp. found that China's manufacturing growth slowed in April, in a further sign that the economy is slowing.
HSBC's monthly purchasing managers' index ? a gauge of business activity ? fell to a worse-than-expected 50.5 from March's 51.6 on a 100-point scale. That means it's growing but only just ? anything below 50 would have signaled a contraction in activity.
"Just as in 2012, Chinese growth is failing to live up to the market's high expectations," said Rebecca O'Keeffe, head of investment at Interactive Investor.
The survey hit Chinese shares particularly hard, with the country's Shanghai Composite Index tumbling 2.6 percent to 2,184.54 and the Shenzhen Composite Index falling 2.7 percent to 923.42. Hong Kong's Hang Seng shed 1.1 percent to 21,806.61.
Elsewhere in Asia, Japan's benchmark Nikkei index slipped as the yen gained ground against the dollar. The Nikkei 225 in Tokyo fell 0.3 percent to close at 13,529.65.
By late afternoon London time, the dollar had recovered, and was trading flat at 99.32 yen. However it was rising against the euro, which was trading 0.3 percent lower at $1.3019.
Oil prices were also depressed following the disappointing economic data, with the benchmark New York rate down $1.08 at $88.11 a barrel.
Source: http://news.yahoo.com/european-rate-cut-hopes-shore-markets-140529624--finance.html
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ISLAMABAD (Reuters) - Pakistani police said on Tuesday they found 45 kg (100 lb) of explosives hidden in a car near the residence where former president Pervez Musharraf is under house arrest, television channels reported.
Video footage showed a bomb disposal squad examining a car near the farmhouse on the edge of the capital Islamabad where the former army chief was detained last week over allegations he had overstepped his powers while in office.
There was no immediate word from police on who they suspected might have planted the explosives.
Pakistan's Taliban movement have threatened to kill Musharraf, who returned from almost four years of self-imposed exile last month in the hope of relaunching his political career at general elections on May 11.
Instead, election officials disqualified him from running and judges ordered he be placed under house arrest to face a hearing next month over allegations he unlawfully ordered the detention of judges in 2007 when he was still in office.
(Reporting By Mehreen Zahra-Malik; Editing by Michael Roddy)
Source: http://news.yahoo.com/pakistan-police-explosives-found-near-musharraf-house-151900508.html
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State Rep. Mike C. Stone (R-NC), left, is being accused this week of pressuring the closure of a weekly radio program at the Central Carolina Community College called ?The Rant.? Stone appears remarkably sensitive as a politician to criticism and contacted the school about the program and its funding. CCCC President T.E. ?Bud? Marchant reportedly responded to the pressure by tossing out any notions of journalistic and academic independence, though he denies the program was shutdown over ?content.?
Stone complained to the college?s president after Stone was criticized for a proposals viewed as injecting more partisanship to the political process. It really does not matter such the subject is. The key was Stone?s response. Stone?s legislative assistant sent CCCC President T.E. ?Bud? Marchant an email asking if the program is affiliated with the college and later demanded to know:
What is their programming schedule and format? Each day, each time slot. What show filled the FCC requirement when they stopped doing The Rant. Or did they stop? Has the show been in production since 2008? What is the radio station?s budget? What is the source of its funding?
Most reputable academic leaders would respond to such a request with a terse reference to the tradition of free speech at academic institutions. Instead, two days later, the CCCC issued an announcement that Marchant had suspended the program.
Stone lists his education as ?Attended, Accounting, Central Carolina Business? and lists his experience as ?Business Owner, O?Connell?s Grocery Store.? He appears to have picked up a taste for power judging from his successful effort to shutdown this program.
As for Marchant, 54, he is the former vice president for Educational Affairs at Piedmont Technical College, Greenwood, S.C. and holds a bachelor?s degree in History/Education from the University of South Carolina and a master?s degree in Administration from Winthrop College. He also holds his Educational Specialist degree from The Citadel and a doctorate in Educational Leadership from the University of Sarasota.
It would be useful if Marchant would explain to the rest of the academic community why he shutdown the program within days of receiving an email from a state legislator if it were not based on ?content? because many would see the alternatives as cowardice or avarice.
Source: Think Progress
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Public release date: 22-Apr-2013 Share ] Contact: Julie Cohen
julie@juliecohen.com
805-455-5021
University of California - Santa Barbara
(Santa Barbara, Calif.) Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of "daughter" cells in Drosophila (fruit flies). The findings appear today in the Proceedings of the National Academy of Sciences.
Denise Montell, Duggan Professor of Molecular, Cellular and Developmental Biology at UCSB, and colleagues studied the ovaries of fruit flies in order to see stem cells in their natural environment. Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology. "It is clear that the fundamental principles that control cell behavior in simple animals are conserved and control the behavior of our cells as well," she said. "There is so much we can learn by studying simple organisms."
Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal. "Having identified this important protein molecule in fruit flies, we can test whether the human version of the protein is important for stem cells and their daughters as well," said Montell. "The more we know about the molecules that govern stem cell behavior, the closer we will get to controlling these cells."
Her research team placed the evolutionarily conserved castor (Cas) gene, which encodes a zinc finger protein, in a genetic circuit with two other evolutionarily conserved genes, hedgehog (Hh) and eyes absent (Eya), to determine the fates of specific cell progeny (daughters). What's more, they identified Cas as a critical, tissue-specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.
The study also shows that complementary patterns of Cas and Eya reveal the gradual differentiation of polar and stalk precursor cells at the earliest stages of their development. In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.
Follicle cells undergo a binary choice during early differentiation. Those that turn into specialized cells found at the poles of egg chambers go on to make two cell types: polar and stalk. The three genes, Cas, Eya and Hh, work in various combinations, sometimes repressively, to determine which types of cells are formed. Cas is required for polar and stalk cell fate specification, while Eya is a negative regulator of these cells' fate. Hh is necessary for Cas to be expressed, and Hh signaling is essential to repress Eya.
"If you just had one of these markers, it was hard to tell what's going on," explained Montell. "All the cells looked the same and you had no idea when or how the process occurred. But now we can actually see how the cells acquire different identities."
Hh also plays many roles in embryonic development, adult homeostasis, birth defects, and cancer. Hh antagonists are currently in clinical trials for the treatment of several types of cancer. However, Hh signaling is important in so many different cell types and tissues that systemic delivery of such inhibitors may cause serious side effects. Therefore identifying the essential, tissue-specific effectors of Hh has the potential to lead to the identification of more specific therapeutic targets.
Someday, targeted inhibition of Hh signaling may be effective in the treatment and prevention of many types of human cancers.
###
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Public release date: 22-Apr-2013 Share ] Contact: Julie Cohen
julie@juliecohen.com
805-455-5021
University of California - Santa Barbara
(Santa Barbara, Calif.) Understanding exactly how stem cells form into specific organs and tissues is the holy grail of regenerative medicine. Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of "daughter" cells in Drosophila (fruit flies). The findings appear today in the Proceedings of the National Academy of Sciences.
Denise Montell, Duggan Professor of Molecular, Cellular and Developmental Biology at UCSB, and colleagues studied the ovaries of fruit flies in order to see stem cells in their natural environment. Because these organisms are excellent models for understanding stem cell biology, researchers were able to shed light on the earliest stages of follicle cell differentiation, a previously poorly understood area of developmental biology. "It is clear that the fundamental principles that control cell behavior in simple animals are conserved and control the behavior of our cells as well," she said. "There is so much we can learn by studying simple organisms."
Using a nuclear protein expressed in follicle stem cells (FSCs), the researchers found that castor, which plays an important role in specifying which types of brain cells are produced during embryonic development, also helps maintain FSCs throughout the life of the animal. "Having identified this important protein molecule in fruit flies, we can test whether the human version of the protein is important for stem cells and their daughters as well," said Montell. "The more we know about the molecules that govern stem cell behavior, the closer we will get to controlling these cells."
Her research team placed the evolutionarily conserved castor (Cas) gene, which encodes a zinc finger protein, in a genetic circuit with two other evolutionarily conserved genes, hedgehog (Hh) and eyes absent (Eya), to determine the fates of specific cell progeny (daughters). What's more, they identified Cas as a critical, tissue-specific target of Hh signaling, which not only plays a key role in maintaining follicle stem cells but also assists in the diversification of their progeny.
The study also shows that complementary patterns of Cas and Eya reveal the gradual differentiation of polar and stalk precursor cells at the earliest stages of their development. In addition, it provides a marker for cell fates and insight into the molecular and cellular mechanisms by which FSC progeny diverge into distinct fates.
Follicle cells undergo a binary choice during early differentiation. Those that turn into specialized cells found at the poles of egg chambers go on to make two cell types: polar and stalk. The three genes, Cas, Eya and Hh, work in various combinations, sometimes repressively, to determine which types of cells are formed. Cas is required for polar and stalk cell fate specification, while Eya is a negative regulator of these cells' fate. Hh is necessary for Cas to be expressed, and Hh signaling is essential to repress Eya.
"If you just had one of these markers, it was hard to tell what's going on," explained Montell. "All the cells looked the same and you had no idea when or how the process occurred. But now we can actually see how the cells acquire different identities."
Hh also plays many roles in embryonic development, adult homeostasis, birth defects, and cancer. Hh antagonists are currently in clinical trials for the treatment of several types of cancer. However, Hh signaling is important in so many different cell types and tissues that systemic delivery of such inhibitors may cause serious side effects. Therefore identifying the essential, tissue-specific effectors of Hh has the potential to lead to the identification of more specific therapeutic targets.
Someday, targeted inhibition of Hh signaling may be effective in the treatment and prevention of many types of human cancers.
###
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2013-04/uoc--usi042213.php
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